Alzheimer's disease is often confused with dementia ~almost identical in effect each are caused differently -symptoms of each differ (yet are misleadingly same or similar to those of other health problems)...
This seeks to explain the difference between Alzheimer's disease and dementia for coping with both better ~with often omitted academic but useful knowledge in layman's terms on Alzheimer's disease and dementia -also some helpful diet and memory stimulating reality-orientation suggestions from various sources on the subject, including exercise for the main side effects of both Dementia and Alzheimer's disease.
Dementias differing on the onset and in progression, not in effect, the essential professional medical consultation involves the elimination of all other possible causes ~because the same effects are caused by and can be due to many other health problems -such as: controllable chemical deficiency e.g. Parkinson's disease; usually treatable severe depression; sometimes curable brain-tumours, strokes or head injuries; completely curable thyroid gland or vitamin deficiency, most infections of the body e.g. kidney infection or pneumonia (and indeed in the older person the effects of sleeping-pills or drugs taken in combination, distressing change or loss in relationships, even changes in usual habits or environment)...
'Dementia' means in Latin 'out of the mind' and was used to be the name given to any and every thing which involved deteriorated mental functions of which the cause of was not know ~indeed the name for schizophrenia (known popularly as 'split personality') of which the sufferers were noticed to be mostly not the elderly at one time was 'dementia praecox' the latter word meaning early or youthful -as in time in many kinds dementia differences came to be noticed as having also to do with or affecting also the biochemical functioning of the nervous system and sometimes the structure of the brain the word 'dementia' has come to refer only to such cases of mainly mental failures where previously the brain was well-formed and faculties were well-functioning (as distinct from by birth, due mostly to oxygen deficiency at the time of birth caused, intellectual inability called 'amentia').
Dementia is, nowadays, the name used for the condition that results to such an exceptional extent in the hardening and thickening and the loss of the elasticity of the blood vessels resulting in inadequate oxygen supply in the blood sometimes also to the brain by the arteries by old age (as a result of cholesterol and saturated fats deposited in them due to neglect in diet and cleansing by proper inhalation and exhalation and exercise) as to, as in the case of only some 10% of those above 70-80 years of age, so abnormally cause cell-death in parts of the brain as results to such an extent of the nervous system's loss of control of one's functions, more so mental, that necessitates medical treatment and aiding by reality-orientation including as to time and space and other persons as well as oneself -mostly manifesting as loss of (first short-term) memory and concentration.
Multi Infarct Dementia, also called 'senile dementia' or 'arterio-sclerotic dementia' or 'vascular dementia', is what is coming increasingly to be meant by the term 'dementia' ~among persons mostly over the age of 75 and exceptionally with such extreme and widespread loss of nerve cells and brain-tissue loss it occurs that it causes deterioration in mental functions affecting mostly memory but sometimes also e.g. judgement and language -it arises from a vascular condition (abnormally high blood pressure ['hypertension'] or some other condition relating to blood vessels ~multiple-sclerosis or e.g. Parkinson's disease or Huntington's chorea may also lead to it) which may be sudden at the onset and with mini strokes destroys small portions of the brain, although for periods of time it may not get worse and even may misleadingly appear to improve; but, as the second most common type of dementia, if the condition is treated it can slow down, even be prevented.
Alzheimer's Disease (the name refers to its discoverer) is a dementia also called 'Alzheimer's sclerosis' (meaning hardening of biological tissue -mostly arteries and nerves) discovered to involve the tangling of tiny threads ('neurofibril' -where molecules of protein 'tau' if incorrectly processed clump together) that run through nerve fibres serving as neural conductors with abnormal concentrations accumulated in them of aluminium, deficiency at neurotransmitter level of an important chemical compound ('acetylcholine') which certain nerve endings release to help transmit electrical impulses, and deteriorated neural matter ('neurotic plaques') around deposits of a kind of protein ('amyloidB') ~atrophy of the brain, the shrinkage, being coupled and probably caused by the hardening of the cover of it as a result, at ages often 40-60 (for which reason it was also called 'pre-senile dementia' or 'pre-senile sclerosis' ~'senile' pertaining to old age when dementia exceptionally occurs), of loss of brain tissue (which unlike the fallacy has nothing to do with under or over use of the brain) -'Pick's disease' being the form of it (otherwise known as 'Pick's convolutional atrophy' where the shrinkage is of the cortex of the brain, in these cases also sometimes with hallucinatory effects and in women sometimes some emotional instability [although science is uncertain if atrophy is not cause but effect]).
This type is some 50% of dementia suffered ~on the outset it is gradual and irreversible brain-cell loss, slow but regular with increasing irritability-anxiety-anger-depression, and in advanced stages unresponsiveness and loss of control of bodily functions as well as immobility leading typically between 5-10 years sometimes 2-20 years later to death -but science is discovering that only in 10% of the cases it is happening before the age 60 where some inherent genetic mutation may be involved (in chromosomes 1 and 14 mostly, and also chromosome 21 [this only to the extent that it causes increased production or depositing of 'amyloidB' forming the core of 'neurotic plaques']) and even then not always on the early onset (as in the case of a defective chromosome 19 [responsible for 'apoliproteinE' used in cholesterol transport]) and 90% of this is after 65 years of age (and that sometimes a drug ['tacrine'] has slowed progression).
Coping with any dementia, including multi infarct dementia, Alzheimer's Disease, without professional medical consultation is not possible and should never be attempted (because dementias differently develop among sufferers) -nor should any drugs be used without professional medical advice (because even 'tacrine' is not in all cases effective, and in some sufferers become toxic to the liver) ~the following are generally agreed by to be helpful in coping with Alzheimer's Disease...
Senses of touch-hearing-sight of the Alzheimer's Disease sufferers deteriorate (sensory impulses are transmitted by nerve tissue [optic thalamus] to sensory areas on sides of the brain); better lighting, definite touches, clearer speech, help much in caring in Alzheimer's Disease...
Perception decrease is common in Alzheimer's Disease (the frontal lobe of the brain controls perception) ~avoid reflective surfaces, shadows (draw curtains at night), confusion (use 24 hour clocks -or marked 'am/pm') for the sufferers of Alzheimer's Disease...
Behavior may change in Alzheimer's Disease (the above may cause dissociative reaction) with wandering at night ~keep busy during day to reasonably tire by night -have a name bracelet and a name and address card in a pocket...
Memory is most affected in Alzheimer's Disease ~first short term memory ('the law of recency' [last learned best remembered] ceases to apply), then long term -but it helps to know and bear in mind that the ability to learn/re-learn continues and reality orientation (a therapy to keep in touch with time-space-people) is simply to often ask and get to say what is doing, how, why, where, what next ('the law of exercise' -repetition aids memory), and to do so nicely ('the law of effect' -stimuli response connection is stronger when consequences are pleasant), and family albums and photographs help greatly in Alzheimer's Disease .
Exercise by swimming, gardening, dancing, walking/strolling (physical functions controlled by the brain [e.g. complex voluntary movements by the frontal lobe] become affected) -and the bladder can be trained. Exercise helps in Alzheimer's disease.
Diet for Alzheimer's Disease should include vitaminB: yeast, peas, fish (lack of it aggravates possible hallucinations), to prevent constipation and de-hydration plenty of water (less salt retains body fluids) and lettuce (a smooth roughage)~also tea and especially coffe in the case of women (more so if 80 or over) has been discovered to help (this is not so for men because of different male and female metabolisms) -caffeine may affect blood-pressure and moderation is suggessted.
Few psychologist considered dementias mental conflicts -now medicine on evidence of biochemical changes consider them an organic syndrome, including Alzheimer's disease.
The diets of approximately 900 older men and women were analyzed over a period of 9 years and blood samples were taken from the participants. It was found that those who had the highest levels of DHA (Docosahexaenoic acid) in their blood reduced their risk of developing dementia by around 47% and Alzheimer's by 39% as compared to those who had low levels of DHA. The study also identified that the levels of DHA in the blood can be influenced by the liver's ability to convert ALA or alpha-linolenic acid, into DHA but that the most significant influence on the amount of DHA in the blood was actually the amount of fish consumed. Those who had the lowest risk consumed 2 or more portions of oily fish a week. It is important to note that this study doesn't prove that eating fish prevents dementia, but the suggestion is that eating fish does seem to reduce the risk.
The link between Omega 3 fatty acids and the brain is well known and research continues to highlight the myriad of ways that these fatty acids impact on brain health in general. One research team from Aberdeen and Edinburgh University in Scotland looked at the Omega 3 intake of around 300 people aged 64 and tested the levels of fatty acids in their blood. They found that those who had supplemented with Omega 3 showed better cognitive processing in mental speed tests and the results were directly related to the level of Omega 3 in their blood. They suggested that Omega 3 might be able to slow down the ageing of the brain itself. If this is the case then Omega 3 fatty acids might have some therapeutic benefit on people who are already suffering from dementia.
Indeed, one study in Sweden looked at the effect that Omega 3 fatty acids had on people who already had Alzheimer's disease. They gave 89 patients a supplement containing DHA and EPA for 6 months and another 85 patients were given a placebo. There was a cross over point at 6 months where the placebo group also began to receive Omega 3. The interesting result from this study was that 32 patients who had mild symptoms of Alzheimer's disease showed less of a decline whilst taking the supplements suggesting that the fatty acids might slow down the progress of the disease in the early stages.
The fatty acid connection ? what do we know?
DHA, along with Eicosapentaenoic acid or EPA are Omega 3 fatty acids found in oily fish such as Salmon, Tuna, Herring, Mackerel and Anchovies. ALA on the other hand is a plant based Omega 3 fatty acid and research has shown that the ability to convert ALA into EPA and DHA is extremely limited in humans and can be even lower than 5%. This means that the only way to get enough EPA and DHA is to eat oily fish or to supplement with fish oil.
The brain is a fatty organ that depends largely on DHA for healthy structure and development. People with Alzheimer's and dementia have been found to have low concentrations of it and the natural assumption would be that increasing the amount of DHA in the diet might have some preventative benefits. However, if there is enough EPA in the diet then the body can produce as much DHA as required so EPA is arguably the most important of the Omega 3 fatty acids. EPA is believed to be the fatty acid mostly responsible for the general functioning of the brain on a day to day basis, and as well as having anti-inflammatory properties, appears to improve the connections in the neural networks in the brain. EPA is also thought to inhibit the activity of the enzyme phospholipase A2 and over-activity of this enzyme has been linked to neurotoxicity and death of brain cells, a feature of Alzheimer's disease and other forms of dementia.
Conclusion
It is too early to say conclusively whether eating more fish or supplementing with fish oil can actually help to prevent dementia and Alzheimer's disease or whether it might slow down degeneration and ageing of the brain but the indications are that it certainly has some influence on brain health, which isn't surprising given that the brain is composed mostly of fat and relies on the omega 3 fatty acids to develop and function properly.
What is known is that fish oil does offer protection against a number of health conditions, including heart disease, circulation problems and even depression so at the very least, supplementing with concentrated fish oil is a convenient way for anyone to boost their physical and mental health in general.
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